Research

Research Lines

  • Cellular and molecular mechanisms implicated in motoneuron degenerative diseases in experimental models. Neuroprotective strategies based on gene and pharmacological therapy.
  • Cell therapy by transplantation of mesenchymal stem cells and neural stem cells for the repair of spinal cord injuries and motoneuron degenerative diseases.
  • Repair of spinal root injuries and pharmacological neuroprotection.
  • Etiopathogenic role of lipid mediators and modulators of the neuroinflammatory response in neurodegeneration induced by central nervous system lesions.
  • Activity-dependent therapies for enhancing axonal regeneration and functional recovery after peripheral nerve lesions and for preventing neuropathic pain.
  • Physiopathologic mechanisms in neuropathic pain induced by nerve and spinal cord lesions.
  • Epigenetic therapy to enhance functional outcome after traumatic injuries of the nervous system.
  • Study of etiopathogenic mechanisms and potential neuroprotective treatments in peripheral neuropathies induced by diabetes and by antitumoral agents.
  • Neuromodulation of neural plasticity for promoting functional restitution in spinal cord injuries.
  • Design and evaluation of neural interfaces for the development of neuroprostheses applied to neurorehabilitation. Study of new intraneural electrodes for the selective stimulation and recording of neural activity.
  • Study of cellular and molecular mechanisms involved in demyelinating diseases.